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Simultaneous Determination of Dioxopromethazine and Phenylephrine in Eye DropsUsing Capillary Isotachophoresis
Izotachoforetické stanovenie dioxoprometazínu vedľa fenylefrínu v očnej instilácii
Dioxoprometazín bol stanovovaný vedľa fenylefrínu v očnej instilácii metódou kapilárnej izotachoforézy.Boli preskúšené dva elektrolytové systémy s rôznym zložením a rôznym pH. Očná instiláciasa pred analýzou riedila vodou v pomere 1 : 50. Bola hodnotená presnosť, správnosť, linearita,robustnosť a selektivita ITP metódy pre obidva systémy.
Klíčová slova:
izotachoforéza – dioxoprometazín – fenylefrín – očná instilácia – validácia
Authors: P. Kubačák; I. Valášková; Emil Havránek
Authors‘ workplace: Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty Univerzity Komenského, Bratislava
Published in: Čes. slov. Farm., 2004; , 89-92
Category:
Overview
Dioxopromethazine and phenylephrine were determined simultaneously in eye drops using themethod of capillary isotachophoresis. Two elektrolyte systems with different compositions and pHwere examinated. Prior to analysis, the eye drops are diluted with water in a ratio 1 : 50. Precision,correctness, linearity, robustness, and selectivity of the ITP method were evaluated for bothelectrolyte sytems.
Key words:
isotachophoresis – dioxopromethazine – phenylephrine – eye drops – validation
Labels
Pharmacy Clinical pharmacology
Article was published inCzech and Slovak Pharmacy
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