PLOS Genetics - Číslo 5/2013


Global Properties and Functional Complexity of Human Gene Regulatory Variation


Side Effects: Substantial Non-Neutral Evolution Flanking Regulatory Sites
From Paramutation to Paradigm

Research Article

Functional Elements Are Embedded in Structurally Constrained Sequences
RNA–Mediated Epigenetic Heredity Requires the Cytosine Methyltransferase Dnmt2
Loss of Expression and Promoter Methylation of SLIT2 Are Associated with Sessile Serrated Adenoma Formation
Attachment Site Selection and Identity in Bxb1 Serine Integrase-Mediated Site-Specific Recombination
Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice
Chromosomal Organization and Segregation in
A Statistical Framework for Joint eQTL Analysis in Multiple Tissues
Cell Polarity and Patterning by PIN Trafficking through Early Endosomal Compartments in
Bck2 Acts through the MADS Box Protein Mcm1 to Activate Cell-Cycle-Regulated Genes in Budding Yeast
High-Resolution Transcriptome Maps Reveal Strain-Specific Regulatory Features of Multiple Isolates
Neuropeptides Function in a Homeostatic Manner to Modulate Excitation-Inhibition Imbalance in
A Compendium of Nucleosome and Transcript Profiles Reveals Determinants of Chromatin Architecture and Transcription
Wnt Signaling Regulates the Lineage Differentiation Potential of Mouse Embryonic Stem Cells through Tcf3 Down-Regulation
Filamin and Phospholipase C-ε Are Required for Calcium Signaling in the Spermatheca
The Specificity and Flexibility of L1 Reverse Transcription Priming at Imperfect T-Tracts
Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations
Implicates Tyrosine-Sulfated Peptide Signaling in Susceptibility and Resistance to Root Infection
Clathrin and AP2 Are Required for Phagocytic Receptor-Mediated Apoptotic Cell Clearance in
Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis
DNA Binding of the Cell Cycle Transcriptional Regulator GcrA Depends on N6-Adenosine Methylation in and Other
From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes
Distinct Translational Control in CD4 T Cell Subsets
Female Bias in and Regulation by the Histone Demethylase KDM6A
ATM–Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response
HDAC7 Is a Repressor of Myeloid Genes Whose Downregulation Is Required for Transdifferentiation of Pre-B Cells into Macrophages
The Majority of Primate-Specific Regulatory Sequences Are Derived from Transposable Elements
Identification of Meiotic Cyclins Reveals Functional Diversification among Plant Cyclin Genes
EGL-13/SoxD Specifies Distinct O and CO Sensory Neuron Fates in
Congruence of Additive and Non-Additive Effects on Gene Expression Estimated from Pedigree and SNP Data
Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits
Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression
Analysis of the Genetic Basis of Disease in the Context of Worldwide Human Relationships and Migration
Duplication and Retention Biases of Essential and Non-Essential Genes Revealed by Systematic Knockdown Analyses
Strong Purifying Selection at Synonymous Sites in
, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein
Chromosome Movements Promoted by the Mitochondrial Protein SPD-3 Are Required for Homology Search during Meiosis
The Secretory Pathway Calcium ATPase PMR-1/SPCA1 Has Essential Roles in Cell Migration during Embryonic Development
The Genomic Signature of Crop-Wild Introgression in Maize
CDK4 T172 Phosphorylation Is Central in a CDK7-Dependent Bidirectional CDK4/CDK2 Interplay Mediated by p21 Phosphorylation at the Restriction Point
Genome-Wide Identification of Regulatory RNAs in the Human Pathogen

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