PLOS Genetics - Číslo 10/2020

Perspective

1008997
How noncrossover homologs are conjoined and segregated in Drosophila male meiosis I: Stable but reversible homolog linkers require a novel Separase target protein

Elsie E. Adams, Qiutao He, Bruce D. McKee


Correction

1009131
Correction: Integrating transcriptomic network reconstruction and eQTL analyses reveals mechanistic connections between genomic architecture and Brassica rapa development

Robert L. Baker, Wen Fung Leong, Marcus T. Brock, Matthew J. Rubin, R. J. Cody Markelz, Stephen Welch, Julin N. Maloof, Cynthia Weinig

1009138
Correction: Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis

Simone Mumbauer, Justine Pascual, Irina Kolotuev, Fisun Hamaratoglu

1009139
Correction: Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma

Guogui Sun, Xiao Ding, Nan Bi, Zhiwu Wang, Lihong Wu, Wei Zhou, Zitong Zhao, Jingbo Wang, Weimin Zhang, Jing Fan, WenJue Zhang, Xin Dong, Ning Lv, Yongmei Song, Qimin Zhan, LuHua Wang


Topic Page

1009034
RNA-directed DNA Methylation

Robert M. Erdmann, Colette L. Picard


Research Article

1008623
Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

Emily E. Wear, Jawon Song, Gregory J. Zynda, Leigh Mickelson-Young, Chantal LeBlanc, Tae-Jin Lee, David O. Deppong, George C. Allen, Robert A. Martienssen, Matthew W. Vaughn, Linda Hanley-Bowdoin, William F. Thompson

1008627
A single Ho-induced double-strand break at the MAT locus is lethal in Candida glabrata

Laetitia Maroc, Youfang Zhou-Li, Stéphanie Boisnard, Cécile Fairhead

1008689
A Rad51-independent pathway promotes single-strand template repair in gene editing

Danielle N. Gallagher, Nhung Pham, Annie M. Tsai, Abigail N. Janto, Jihyun Choi, Grzegorz Ira, James E. Haber

1008718
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Suzanne Vogelezang, Jonathan P. Bradfield, Tarunveer S. Ahluwalia, John A. Curtin, Timo A. Lakka, Niels Grarup, Markus Scholz, Peter J. van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O. Fedko, Natalia Vilor-Tejedor, Diana L. Cousminer, Marie Standl, Carol A. Wang, Jorma Viikari, Frank Geller, Carmen Iñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bacelis, Loic Yengo, Maties Torrent, Ioanna Ntalla, Øyvind Helgeland, Saskia Selzam, Judith M. Vonk, Mohammed H. Zafarmand, Barbara Heude, Ismaa Sadaf Farooqi, Akram Alyass, Robin N. Beaumont, Christian T. Have, Peter Rzehak, Jose Ramon Bilbao, Theresia M. Schnurr, Inês Barroso, Klaus Bønnelykke, Lawrence J. Beilin, Lisbeth Carstensen, Marie-Aline Charles, Bo Chawes, Karine Clément, Ricardo Closa-Monasterolo, Adnan Custovic, Johan G. Eriksson, Joaquin Escribano, Maria Groen-Blokhuis, Veit Grote, Dariusz Gruszfeld, Hakon Hakonarson, Torben Hansen, Andrew T. Hattersley, Mette Hollensted, Jouke-Jan Hottenga, Elina Hyppönen, Stefan Johansson, Raimo Joro, Mika Kähönen, Ville Karhunen, Wieland Kiess, Bridget A. Knight, Berthold Koletzko, Andreas Kühnapfel, Kathrin Landgraf, Jean-Paul Langhendries, Terho Lehtimäki, Jaakko T. Leinonen, Aihuali Li, Virpi Lindi, Estelle Lowry, Mariona Bustamante, Carolina Medina-Gomez, Mads Melbye, Kim F. Michaelsen, Camilla S. Morgen, Trevor A. Mori, Tenna R. H. Nielsen, Harri Niinikoski, Albertine J. Oldehinkel, Katja Pahkala, Kalliope Panoutsopoulou, Oluf Pedersen, Craig E. Pennell, Christine Power, Sijmen A. Reijneveld, Fernando Rivadeneira, Angela Simpson, Peter D. Sly, Jakob Stokholm, Kook K. Teo, Elisabeth Thiering, Nicholas J. Timpson, André G. Uitterlinden, Catharina E. M. van Beijsterveldt, Barbera D. C. van Schaik, Marc Vaudel, Elvira Verduci, Rebecca K. Vinding, Mandy Vogel, Eleftheria Zeggini, Sylvain Sebert, Mads V. Lind, Christopher D. Brown, Loreto Santa-Marina, Eva Reischl, Christine Frithioff-Bøjsøe, David Meyre, Eleanor Wheeler, Ken Ong, Ellen A. Nohr, Tanja G. M. Vrijkotte, Gerard H. Koppelman, Robert Plomin, Pål R. Njølstad, George D. Dedoussis, Philippe Froguel, Thorkild I. A. Sørensen, Bo Jacobsson, Rachel M. Freathy, Babette S. Zemel, Olli Raitakari, Martine Vrijheid, Bjarke Feenstra, Leo-Pekka Lyytikainen, Harold Snieder, Holger Kirsten, Patrick G. Holt, Joachim Heinrich, Elisabeth Widén, Jordi Sunyer, Dorret I. Boomsma, Marjo-Riitta Jarvelin, Antje Körner, George Davey Smith, Jens-Christian Holm, Mustafa Atalay, Clare Murray, Hans Bisgaard, Mark I. McCarthy, , Vincent W. V. Jaddoe, Struan F. A. Grant, Janine F. Felix

1008751
C. elegans CLASP/CLS-2 negatively regulates membrane ingression throughout the oocyte cortex and is required for polar body extrusion

Aleesa J. Schlientz, Bruce Bowerman

1008821
The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress

Sarel J. Urso, Marcella Comly, John A. Hanover, Todd Lamitina

1008928
Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO

Joe Weber, Zeynep Kabakci, Soumya Chaurasia, Erich Brunner, Christian F. Lehner

1009016
Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion

Katalin Goda, Yaprak Dönmez-Cakil, Szabolcs Tarapcsák, Gábor Szalóki, Dániel Szöllősi, Zahida Parveen, Dóra Türk, Gergely Szakács, Peter Chiba, Thomas Stockner

1009033
Dbp5 associates with RNA-bound Mex67 and Nab2 and its localization at the nuclear pore complex is sufficient for mRNP export and cell viability

Rebecca L. Adams, Susan R. Wente

1009035
The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations

Fredrika Åsenius, Tyler J. Gorrie-Stone, Ama Brew, Yasmin Panchbhaya, Elizabeth Williamson, Leonard C. Schalkwyk, Vardhman K. Rakyan, Michelle L. Holland, Sarah J. Marzi, David J. Williams

1009037
A cautionary note on the use of unsupervised machine learning algorithms to characterise malaria parasite population structure from genetic distance matrices

James A. Watson, Aimee R. Taylor, Elizabeth A. Ashley, Arjen Dondorp, Caroline O. Buckee, Nicholas J. White, Chris C. Holmes

1009042
Selection for ancient periodic motifs that do not impart DNA bending

Aletheia Atzinger, Jeffrey G. Lawrence

1009046
The Ccr4-Not complex regulates TORC1 signaling and mitochondrial metabolism by promoting vacuole V-ATPase activity

Hongfeng Chen, P. Winston Miller, Daniel L. Johnson, R. Nicholas Laribee

1009052
Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function

Kade M. Power, Jyothi S. Akella, Amanda Gu, Jonathon D. Walsh, Sebastian Bellotti, Margaret Morash, Winnie Zhang, Yasmin H. Ramadan, Nicole Ross, Andy Golden, Harold E. Smith, Maureen M. Barr, Robert O’Hagan

1009054
Phenotype-genotype comorbidity analysis of patients with rare disorders provides insight into their pathological and molecular bases

Elena Díaz-Santiago, Fernando M. Jabato, Elena Rojano, Pedro Seoane, Florencio Pazos, James R. Perkins, Juan A. G. Ranea

1009068
Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen

Jie Liu, Zehua Zuo, Meijuan Zou, Toren Finkel, Shihui Liu

1009069
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function

Constanze M. Hammerle, Ionel Sandovici, Gemma V. Brierley, Nicola M. Smith, Warren E. Zimmer, Ilona Zvetkova, Haydn M. Prosser, Yoichi Sekita, Brian Y. H. Lam, Marcella Ma, Wendy N. Cooper, Antonio Vidal-Puig, Susan E. Ozanne, Gema Medina-Gómez, Miguel Constância

1009070
PE homeostasis rebalanced through mitochondria-ER lipid exchange prevents retinal degeneration in Drosophila

Haifang Zhao, Tao Wang

1009076
Chromosome number evolves at equal rates in holocentric and monocentric clades

Sarah N. Ruckman, Michelle M. Jonika, Claudio Casola, Heath Blackmon

1009082
Disentangling the determinants of transposable elements dynamics in vertebrate genomes using empirical evidences and simulations

Yann Bourgeois, Robert Ruggiero, Imtiyaz Hariyani, Stéphane Boissinot, Robert P. Ruggiero, Imtiyaz Hariyani, Stéphane Boissinot

1009087
Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing

Kashyap Chhatbar, Justyna Cholewa-Waclaw, Ruth Shah, Adrian Bird, Guido Sanguinetti

1009097
Diversified regulation of circadian clock gene expression following whole genome duplication

Alexander C. West, Marianne Iversen, Even H. Jørgensen, Simen R. Sandve, David G. Hazlerigg, Shona H. Wood

1009103
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling

Khairunnisa Mentari Semesta, Ruilin Tian, Martin Kampmann, Mark von Zastrow, Nikoleta G. Tsvetanova

1009140
Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes

Zhaoxia Dai, Dong Li, Xiao Du, Ying Ge, Deborah A. Hursh, Xiaolin Bi


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