The association between heat exposure and hospitalization for undernutrition in Brazil during 2000−2015: A nationwide case-crossover study

Autoři: Rongbin Xu aff001;  Qi Zhao aff002;  Micheline S. Z. S. Coelho aff003;  Paulo H. N. Saldiva aff003;  Michael J. Abramson aff002;  Shanshan Li aff002;  Yuming Guo aff001
Působiště autorů: Department of Epidemiology, School of Public Health and Management, Binzhou Medical University, Yantai, Shandong, China aff001;  Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia aff002;  Institute of Advanced Studies, University of São Paulo, São Paulo, Brazil aff003
Vyšlo v časopise: The association between heat exposure and hospitalization for undernutrition in Brazil during 2000−2015: A nationwide case-crossover study. PLoS Med 16(10): e32767. doi:10.1371/journal.pmed.1002950
Kategorie: Research Article
doi: 10.1371/journal.pmed.1002950



Global warming is predicted to indirectly result in more undernutrition by threatening crop production. Whether temperature rise could affect undernutrition directly is unknown. We aim to quantify the relationship between short-term heat exposure and risk of hospitalization due to undernutrition in Brazil.

Methods and findings

We collected hospitalization and weather data for the hot season (the 4 adjacent hottest months for each city) from 1,814 Brazilian cities during 1 January 2000−31 December 2015. We used a time-stratified case-crossover design to quantify the association between heat exposure and hospitalization due to undernutrition. Region-specific odds ratios (ORs) were used to calculate the attributable fractions (AFs). A total of 238,320 hospitalizations for undernutrition were recorded during the 2000−2015 hot seasons. Every 1°C increase in daily mean temperature was associated with a 2.5% (OR 1.025, 95% CI 1.020−1.030, p < 0.001) increase in hospitalizations for undernutrition across lag 0–7 days. The association was greatest for individuals aged ≥80 years (OR 1.046, 95% CI 1.034−1.059, p < 0.001), 0–4 years (OR 1.039, 95% CI 1.024–1.055, p < 0.001), and 5–19 years (OR 1.042, 95% CI 1.015–1.069, p = 0.002). Assuming a causal relationship, we estimate that 15.6% of undernutrition hospitalizations could be attributed to heat exposure during the study period. The AF grew from 14.1% to 17.5% with a 1.1°C increase in mean temperature from 2000 to 2015. The main limitations of this study are misclassification of different types of undernutrition, lack of individual temperature exposure data, and being unable to adjust for relative humidity.


Our study suggests that global warming might directly increase undernutrition morbidity, by a route other than by threatening food security. This short-term effect is increasingly important with global warming. Global strategies addressing the syndemic of climate change and undernutrition should focus not only on food systems, but also on the prevention of heat exposure.

Klíčová slova:

Brazil – Climate change – Geriatrics – Global warming – Humidity – Malnutrition – Morbidity – Seasons


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PLOS Medicine

2019 Číslo 10

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