The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials


Autoři: Andrew Vernon aff001;  Katherine Fielding aff002;  Rada Savic aff004;  Lori Dodd aff005;  Payam Nahid aff006
Působiště autorů: Clinical Research Branch, Division of TB Elimination, NCHHSTP, US Centers for Disease Control & Prevention, Atlanta, Georgia, United States of America aff001;  TB Centre, London School of Hygiene & Tropical Medicine, London, United Kingdom aff002;  Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa aff003;  Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, United States of America aff004;  National Institute for Allergy and Infectious Disease, National Institutes of Health, Washington DC, United States of America aff005;  Division of Pulmonary and Critical Care Medicine, University of California, San Francisco at San Francisco General Hospital, San Francisco, California, United States of America aff006
Vyšlo v časopise: The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials. PLoS Med 16(12): e32767. doi:10.1371/journal.pmed.1002884
Kategorie: Collection Review
doi: 10.1371/journal.pmed.1002884

Souhrn

Andrew Vernon and co-authors discuss adherence to therapy and its measurement in tuberculosis treatment trials.

Klíčová slova:

Clinical trials – Drug adherence – Drug metabolism – Drug screening – Ingestion – Pharmacokinetics – Tuberculosis – Urine


Zdroje

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Interní lékařství

Článek vyšel v časopise

PLOS Medicine


2019 Číslo 12

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