Antibody-based therapies for COVID-19: Can Europe move faster?


Autoři: Michel D. Kazatchkine aff001;  Michel Goldman aff002;  Jean-Louis Vincent aff003
Působiště autorů: Global Health Center, Graduate Institute, Geneva, Switzerland aff001;  I3h Institute, Université libre de Bruxelles, Brussels, Belgium aff002;  Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium aff003
Vyšlo v časopise: Antibody-based therapies for COVID-19: Can Europe move faster?. PLoS Med 17(5): e32767. doi:10.1371/journal.pmed.1003127
Kategorie: Perspective
doi: 10.1371/journal.pmed.1003127

Souhrn

Michel Goldman and colleagues call on the European medical and scientific community to coordinate efforts on immunotherapy-based approaches to coronavirus.

Klíčová slova:

Antibodies – Blood plasma – Europe – European Union – Immunology – Respiratory infections – Immunotherapy – Antibody therapy


Zdroje

1. Vincent JL, Taccone FS. Understanding pathways to death in patients with COVID-19. Lancet Respir Med 2020. Published online April 6, 2020.https://doi.org/10.1016/S2213-2600(20)30165-X

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3. Ju B, Zhang Q, Ge X, Wang R, Yu J, Shan S, et al. Potent human neutralizing antibodies elicited by SARS-CoV-2 infection. BioRxiv https://doi.org/10.1101/2020.03.21.990770

4. Bao L, Deng W, Gao H, Xiao C, Liu J, Xue J, et al. Reinfection could not occur in SARS-CoV-2 infected rhesus macaques. BioRxiv https://doi.org/10.1101/2020.03.13.990226

5. Temperton NJ, Chan PK, Simmons G, Zambon MC, Tedder RS, Takeuchi Y, et al. Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes. Emerg Infect Dis 2015; 11:411–16.

6. Shen C, Wang Z, Zhao F, Yang Y, Li J, Yuan J et al. Treatment of 5 critically ill patients with COVID-19 with convalescent plasma. JAMA 2020; Published online March 27, 2020. doi: 10.1001/jama.2020.4783

7. Roback JD, Guarner J. Convalescent plasma to treat Covid-19. JAMA 2020; Published on line March27, 2020. doi: 10.1001/jama.2020.4940 32219429

8. Zhou B, Zhong N, Guan Y. Treatment with convalescent plasma for influenza A (H5N1) infection. N Engl J Med 2007; 357: 1450–51 doi: 10.1056/NEJMc070359 17914053

9. Bal C, Herbreteau C, Buchy P, Rith S, Zaid M, Kristanto W et al. Safety, potential efficacy, and pharmacokinetics of specific polyclonal immunoglobulin F(ab’)2 fragments against avian influenza A (H5N1) in healthy volunteers: a single-centre, randomised, double-blind, placebo-controlled, phase 1 study. Lancet Infect Dis 2015; 15:285–92. doi: 10.1016/S1473-3099(14)71072-2 25662592

10. Coughlin MM, Lou G, Martinez O, Masterman SK, Olsen OA, Moksa AA et al. Generation and characterization of human monoclonal neutralizing antibodies with distinct binding and sequence features against SARS coronavirus using XenoMouse. Virology 2007; 361: 93–102. doi: 10.1016/j.virol.2006.09.029 17161858

11. Mulangu S, Dodd LE, Davey RT et al. A randomized, controlled trial of Ebola virus disease therapeutics. N Engl J Med 2019; 381:2293–2303 doi: 10.1056/NEJMoa1910993 31774950

Štítky
Interní lékařství

Článek vyšel v časopise

PLOS Medicine


2020 Číslo 5

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