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PLOS Genetics - Číslo 11/2011

Research Article

32767

Duplication Hotspots Are Associated with Late-Replicating Regions of the Genome

De Novo Origin of Human Protein-Coding Genes

Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells

Short Day–Mediated Cessation of Growth Requires the Downregulation of AINTEGUMENTALIKE1 Transcription Factor in Hybrid Aspen

Physiological IRE-1-XBP-1 and PEK-1 Signaling in Larval Development and Immunity

Role of Pirh2 in Mediating the Regulation of p53 and c-Myc

Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution

FOXO Regulates Organ-Specific Phenotypic Plasticity In

Heritable Epigenetic Variation among Maize Inbreds

Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

Attenuation of the Sensing Capabilities of PhoQ in Transition to Obligate Insect–Bacterial Association

A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened

Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in -Induced Senescence

Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks

The SUN Protein Mps3 Is Required for Spindle Pole Body Insertion into the Nuclear Membrane and Nuclear Envelope Homeostasis

Evidence-Based Annotation of Gene Function in MR-1 Using Genome-Wide Fitness Profiling across 121 Conditions

Effect of Host Species on the Distribution of Mutational Fitness Effects for an RNA Virus

Pch2 Acts through Xrs2 and Tel1/ATM to Modulate Interhomolog Bias and Checkpoint Function during Meiosis

SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression

from the Aphid : A Missing Link from Facultative to Obligate Insect Endosymbiont

Recessive Antimorphic Alleles Overcome Functionally Redundant Loci to Reveal Function in Flowers and Meristems

Over-Expression of DSCAM and COL6A2 Cooperatively Generates Congenital Heart Defects

Consequences of Eukaryotic Enhancer Architecture for Gene Expression Dynamics, Development, and Fitness

Distinct Genetic Architectures for Male and Female Inflorescence Traits of Maize

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

PcG Complexes Set the Stage for Epigenetic Inheritance of Gene Silencing in Early S Phase before Replication

The Gene Contains Hotspots for L1 Endonuclease-Dependent Insertion

Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes

Multiple Means to the Same End: The Genetic Basis of Acquired Stress Resistance in Yeast

Genome-Wide Crossover Distribution in Meiosis Reveals Sex-Specific Patterns along Chromosomes

TRY-5 Is a Sperm-Activating Protease in Seminal Fluid

Homologs of Retinoblastoma-Associated Protein 46/48 Associate with a Histone Deacetylase to Act Redundantly in Chromatin Silencing

Genetic Interaction Maps in Reveal Functional Crosstalk among Cell Envelope Biogenesis Pathways

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

Perspective

32767

De Novo Origins of Human Genes

For Male , Sperm Activation Is a “Just-in-Time” Event

PLOS Genetics

2011 Číslo 11

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