PLOS Genetics - Číslo 11/2020

Formal Comment

1009059
Formal commentary

Gustavo D. Aguirre, Hannes Lohi, Maria Kaukonen, Leonardo Murgiano


Research Article

1008802
A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population

Catherine Tcheandjieu, Matthew Aguirre, Stefan Gustafsson, Priyanka Saha, Praneetha Potiny, Melissa Haendel, Erik Ingelsson, Manuel A. Rivas, James R. Priest

1008913
Mms19 promotes spindle microtubule assembly in Drosophila neural stem cells

Rohan Chippalkatti, Boris Egger, Beat Suter

1009049
Genotype imputation using the Positional Burrows Wheeler Transform

Simone Rubinacci, Olivier Delaneau, Jonathan Marchini

1009067
The DNA damage response is required for oocyte cyst breakdown and follicle formation in mice

Ana Martínez-Marchal, Yan Huang, Maria Teresa Guillot-Ferriols, Mònica Ferrer-Roda, Anna Guixé, Montserrat Garcia-Caldés, Ignasi Roig

1009084
Loss of hepatocyte cell division leads to liver inflammation and fibrosis

Matthew R. Dewhurst, Jin Rong Ow, Gözde Zafer, Noémi K. M. van Hul, Heike Wollmann, Xavier Bisteau, David Brough, Hyungwon Choi, Philipp Kaldis

1009090
A genetic variant controls interferon-β gene expression in human myeloid cells by preventing C/EBP-β binding on a conserved enhancer

Anaïs Assouvie, Maxime Rotival, Juliette Hamroune, Didier Busso, Paul-Henri Romeo, Lluís Quintana-Murci, Germain Rousselet

1009101
Identity-by-descent with uncertainty characterises connectivity of Plasmodium falciparum populations on the Colombian-Pacific coast

Aimee R. Taylor, Diego F. Echeverry, Timothy J. C. Anderson, Daniel E. Neafsey, Caroline O. Buckee

1009104
A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse

Ines Leca, Alexander Phillips, Iris Hofer, Lukas Landler, Lyubov Ushakova, Thomas David Cushion, Gerhard Dürnberger, Karel Stejskal, Karl Mechtler, David Anthony Keays, Alexander William Phillips

1009105
Inferring causal direction between two traits in the presence of horizontal pleiotropy with GWAS summary data

Haoran Xue, Wei Pan

1009106
A complementary study approach unravels novel players in the pathoetiology of Hirschsprung disease

Tanja Mederer, Stefanie Schmitteckert, Julia Volz, Cristina Martínez, Ralph Röth, Thomas Thumberger, Volker Eckstein, Jutta Scheuerer, Cornelia Thöni, Felix Lasitschka, Leonie Carstensen, Patrick Günther, Stefan Holland-Cunz, Robert Hofstra, Erwin Brosens, Jill A. Rosenfeld, Christian P. Schaaf, Duco Schriemer, Isabella Ceccherini, Marta Rusmini, Joseph Tilghman, Berta Luzón-Toro, Ana Torroglosa, Salud Borrego, Clara Sze-man Tang, Mercè Garcia-Barceló, Paul Tam, Nagarajan Paramasivam, Melanie Bewerunge-Hudler, Carolina De La Torre, Norbert Gretz, Gudrun A. Rappold, Philipp Romero, Beate Niesler

1009110
Unique genetic signatures of local adaptation over space and time for diapause, an ecologically relevant complex trait, in Drosophila melanogaster

Priscilla A. Erickson, Cory A. Weller, Daniel Y. Song, Alyssa S. Bangerter, Paul Schmidt, Alan O. Bergland

1009121
A frog with three sex chromosomes that co-mingle together in nature: Xenopus tropicalis has a degenerate W and a Y that evolved from a Z chromosome

Benjamin L. S. Furman, Caroline M. S. Cauret, Martin Knytl, Xue-Ying Song, Tharindu Premachandra, Caleb Ofori-Boateng, Danielle C. Jordan, Marko E. Horb, Ben J. Evans

1009128
The Bric-à-Brac BTB/POZ transcription factors are necessary in niche cells for germline stem cells establishment and homeostasis through control of BMP/DPP signaling in the Drosophila melanogaster ovary

Laurine Miscopein Saler, Virginie Hauser, Mathieu Bartoletti, Charlotte Mallart, Marianne Malartre, Laura Lebrun, Anne-Marie Pret, Laurent Théodore, Fabienne Chalvet, Sophie Netter

1009129
A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics

Daniel C. Maddison, Mónica Alfonso-Núñez, Aisha M. Swaih, Carlo Breda, Susanna Campesan, Natalie Allcock, Anna Straatman-Iwanowska, Charalambos P. Kyriacou, Flaviano Giorgini

1009161
No association between SCN9A and monogenic human epilepsy disorders

James Fasham, Joseph S. Leslie, Jamie W. Harrison, James Deline, Katie B. Williams, Ashley Kuhl, Jessica Scott Schwoerer, Harold E. Cross, Andrew H. Crosby, Emma L. Baple

1009163
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth

Yunpeng Wang, Ron Nudel, Michael E. Benros, Kristin Skogstrand, Simon Fishilevich, , Doron Lancet, Jiangming Sun, David M. Hougaard, Ole A. Andreassen, Preben Bo Mortensen, Alfonso Buil, Thomas F. Hansen, Wesley K. Thompson, Thomas Werge

1009168
In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor

Hui Hong, Shun Yao, Yuanyuan Zhang, Yi Ye, Cheng Li, Liang Hu, Yihua Sun, Hsin-Yi Huang, Hongbin Ji, Liang Hu

1009172
Suppression of retinal degeneration by two novel ERAD ubiquitin E3 ligases SORDD1/2 in Drosophila

Jaiwei Xu, Haifang Zhao, Tao Wang

1009175
Stability of SARS-CoV-2 phylogenies

Yatish Turakhia, Nicola De Maio, Bryan Thornlow, Landen Gozashti, Robert Lanfear, Conor R. Walker, Angie S. Hinrichs, Jason D. Fernandes, Rui Borges, Greg Slodkowicz, Lukas Weilguny, David Haussler, Nick Goldman, Russell Corbett-Detig

1009176
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors

Emily M. Schleicher, Ashna Dhoonmoon, Lindsey M. Jackson, Kristen E. Clements, Coryn L. Stump, Claudia M. Nicolae, George-Lucian Moldovan

1009180
Genetic engineering of sex chromosomes for batch cultivation of non-transgenic, sex-sorted males

Siba R. Das, Maciej Maselko, Ambuj Upadhyay, Michael J. Smanski

1009182
Differential transcript usage in the Parkinson’s disease brain

Fiona Dick, Gonzalo S. Nido, Guido Werner Alves, Ole-Bjørn Tysnes, Gry Hilde Nilsen, Christian Dölle, Charalampos Tzoulis

1009183
The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation

Franck Chesnel, Anne Couturier, Adrien Alusse, Jean-Philippe Gagné, Guy G. Poirier, Dominique Jean, François-Michel Boisvert, Pauline Hascoet, Luc Paillard, Yannick Arlot-Bonnemains, Xavier Le Goff

1009184
Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis

Damien Garrido, Mohammed Bourouh, Éric Bonneil, Pierre Thibault, Andrew Swan, Vincent Archambault

1009185
Opposing functions of Fng1 and the Rpd3 HDAC complex in H4 acetylation in Fusarium graminearum

Hang Jiang, Aliang Xia, Meng Ye, Jingyi Ren, Dongao Li, Huiquan Liu, Qinhu Wang, Ping Lu, Chunlan Wu, Jin-Rong Xu, Cong Jiang

1009187
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation

Lene Clausen, Amelie Stein, Martin Grønbæk-Thygesen, Lasse Nygaard, Cecilie L. Søltoft, Sofie V. Nielsen, Michael Lisby, Tommer Ravid, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

1009188
A C. elegans Zona Pellucida domain protein functions via its ZPc domain

Jennifer D. Cohen, Jessica G. Bermudez, Matthew C. Good, Meera V. Sundaram

1009192
Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function

Brittany A. Martínez, Rosalie G. Hoyle, Scott Yeudall, Mitchell E. Granade, Thurl E. Harris, J. David Castle, Norbert Leitinger, Michelle L. Bland

1009194
Gtsf1 is essential for proper female sex determination and transposon silencing in the silkworm, Bombyx mori

Kai Chen, Ye Yu, Dehong Yang, Xu Yang, Linmeng Tang, Yujia Liu, Xingyu Luo, James R. Walter, Zulian Liu, Jun Xu, Yongping Huang

1009196
TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8AKT1/SGK1 define separate branches of the stress response mechanisms in fission yeast

Emese Pataki, LubFtablea Simhaev, Hamutal Engel, Adiel Cohen, Martin Kupiec, Ronit Weisman, Luba Simhaev

1009197
NIGT1 family proteins exhibit dual mode DNA recognition to regulate nutrient response-associated genes in Arabidopsis

Yoshiaki Ueda, Shohei Nosaki, Yasuhito Sakuraba, Takuya Miyakawa, Takatoshi Kiba, Masaru Tanokura, Shuichi Yanagisawa

1009198
Oxidative stress antagonizes fluoroquinolone drug sensitivity via the SoxR-SUF Fe-S cluster homeostatic axis

Audrey Gerstel, Jordi Zamarreño Beas, Yohann Duverger, Emmanuelle Bouveret, Frédéric Barras, Béatrice Py

1009200
A spectrum of verticality across genes

Falk S. P. Nagies, Julia Brueckner, Fernando D. K. Tria, William F. Martin


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