proLékárníky.cz / Odborné časopisy / PLOS Genetics / 2020 - 6

Lack of reproducibility in osteocalcin-deficient mice

English version

Autoři: Takeshi Moriishi aff001;  Toshihisa Komori aff002
Působiště autorů: Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan aff001;  Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan aff002
Vyšlo v časopise: Lack of reproducibility in osteocalcin-deficient mice. PLoS Genet 16(6): e32767. doi:10.1371/journal.pgen.1008939
Kategorie: Formal Comment
doi: 10.1371/journal.pgen.1008939

Zdroje

1. Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, et al. Increased bone formation in osteocalcin-deficient mice. Nature. 1996;382(6590):448–52. Epub 1996/08/01. doi: 10.1038/382448a0 8684484.

2. Moriishi T, Ozasa R, Ishimoto T, Nakano T, Hasegawa T, Miyazaki T, et al. Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass. PLoS Genet. 2020;16(5):e1008586. Epub 2020/05/29. doi: 10.1371/journal.pgen.1008586 32463816.

3. Diegel CR, Hann S, Ayturk UM, Hu JCW, Lim KE, Droscha CJ, et al. An osteocalcin-deficient mouse strain without endocrine abnormalities. PLoS Genet. 2020;16(5):e1008361. Epub 2020/05/29. doi: 10.1371/journal.pgen.1008361 32463812.

4. Bailey S, Karsenty G, Gundberg C, Vashishth D. Osteocalcin and osteopontin influence bone morphology and mechanical properties. Ann N Y Acad Sci. 2017;1409(1):79–84. Epub 2017/10/19. doi: 10.1111/nyas.13470 29044594; PubMed Central PMCID: PMC5730490.

5. Ducy P, Starbuck M, Priemel M, Shen J, Pinero G, Geoffroy V, et al. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. Genes Dev. 1999;13(8):1025–36. Epub 1999/04/24. doi: 10.1101/gad.13.8.1025 10215629; PubMed Central PMCID: PMC316641.

6. Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, et al. Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency. Dev Dyn. 2007;236(7):1876–90. Epub 2007/05/15. doi: 10.1002/dvdy.21187 17497678.

7. Vella A, Kumar R. Osteocalcin and the Regulation of Glucose Metabolism. Clin Rev Bone Miner Metab. 2013;11(1):11–6. Epub 2013/03/01. doi: 10.1007/s12018-012-9126-x 26109922; PubMed Central PMCID: PMC4476242.

8. Gundberg CM, Lian JB, Booth SL. Vitamin K-dependent carboxylation of osteocalcin: friend or foe? Adv Nutr. 2012;3(2):149–57. Epub 2012/04/21. doi: 10.3945/an.112.001834 22516722; PubMed Central PMCID: PMC3648715 interest.

9. Tura A, Pacini G, Yamada Y, Seino Y, Ahrén B. Glucagon and insulin secretion, insulin clearance, and fasting glucose in GIP receptor and GLP-1 receptor knockout mice. Am J Physiol Regul Integr Comp Physiol. 2019;316(1):R27–r37. Epub 2018/11/22. doi: 10.1152/ajpregu.00288.2018 30462524.

10. Nicholson A, Reifsnyder PC, Malcolm RD, Lucas CA, MacGregor GR, Zhang W, et al. Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene. Obesity (Silver Spring, Md). 2010;18(10):1902–5. Epub 2010/01/09. doi: 10.1038/oby.2009.477 20057372; PubMed Central PMCID: PMC2888716.

Článek Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses
Článek Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase
Článek Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis
Článek Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade
Článek Osteocalcin promotes bone mineralization but is not a hormone
Článek A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5
Článek Integrins regulate epithelial cell shape by controlling the architecture and mechanical properties of basal actomyosin networks
Článek Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism
Článek NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure
Článek Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves
Článek Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology
Článek Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptations
Článek Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease
Článek Exclusive breastfeeding can attenuate body-mass-index increase among genetically susceptible children: A longitudinal study from the ALSPAC cohort
Článek Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development
Článek BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1
Článek MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progression
Článek Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass
Článek In vivo modeling of metastatic human high-grade serous ovarian cancer in mice
Článek GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation
Článek The role of ROC75 as a daytime component of the circadian oscillator in Chlamydomonas reinhardtii
Článek An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons
Článek BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor
Článek Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3′UTR intron-containing NMD targets
Článek Behavioral and brain- transcriptomic synchronization between the two opponents of a fighting pair of the fish Betta splendens
Článek Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape
Článek Control of mRNA translation by dynamic ribosome modification
Článek ROS regulation of RAS and vulva development in Caenorhabditis elegans
Článek The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae
Článek yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development
Článek Overlapping functions and protein-protein interactions of LRR-extensins in Arabidopsis
Článek Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections
Článek The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants
Článek Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation
Článek Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits
Článek Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity
Článek A Bayesian method to estimate variant-induced disease penetrance
Článek NatB regulates Rb mutant cell death and tumor growth by modulating EGFR/MAPK signaling through the N-end rule pathways
Článek ­­­­­­Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
Článek Phylogenetic background and habitat drive the genetic diversification of Escherichia coli
Článek VolcanoFinder: Genomic scans for adaptive introgression
Článek Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction
Článek Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)
Článek Suppression of class I compensated cell enlargement by xs2 mutation is mediated by salicylic acid signaling
Článek Protein-protein interaction network controlling establishment and maintenance of switchable cell polarity
Článek Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes
Článek Regulation of epithelial integrity and organ growth by Tctp and Coracle in Drosophila
Článek The brachyceran de novo gene PIP82, a phosphorylation target of aPKC, is essential for proper formation and maintenance of the rhabdomeric photoreceptor apical domain in Drosophila
Článek Reciprocal regulation between nicotinamide adenine dinucleotide metabolism and abscisic acid and stress response pathways in Arabidopsis
Článek c-di-GMP inhibits LonA-dependent proteolysis of TfoY in Vibrio cholerae
Článek All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders
Článek Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophase
Článek Nitric oxide mediates neuro-glial interaction that shapes Drosophila circadian behavior
Článek JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage
Článek Age-of-onset information helps identify 76 genetic variants associated with allergic disease
Článek Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genes cooperatively with Hmo1 in Saccharomyces cerevisiae
Článek AXR1 affects DNA methylation independently of its role in regulating meiotic crossover localization
Článek The facts of the matter: What is a hormone?
Článek Independent validation of experimental results requires timely and unrestricted access to animal models and reagents
Článek vyšel v časopise

PLOS Genetics

2020 Číslo 6
Nejčtenější tento týden
Nejčtenější v tomto čísle
Kurzy

Zvyšte si kvalifikaci online z pohodlí domova

Třikrát z interní medicíny
nový kurz
Autoři: MUDr. Jana Kubátová
Pokročilá Parkinsonova nemoc − úskalí a možnosti léčby
Autoři: doc. MUDr. Marek Baláž, Ph.D.
Léčba diabetes mellitus 2. typu pomocí GLP- 1 RA
Depresivní porucha a zánětlivé procesy
Autoři: MUDr. Juraj Tkáč
Methotrexát a jeho formy podávání v revmatologii
Autoři: MUDr. Liliana Šedová
Všechny kurzy
Přihlášení
Zapomenuté heslo

Zadejte e-mailovou adresu, se kterou jste vytvářel(a) účet, budou Vám na ni zaslány informace k nastavení nového hesla.

Přihlášení

Nemáte účet?  Registrujte se